Acute effect of proprotein convertase subtilisin/kexin type 9 inhibitor on oxidized low-density lipoprotein and lipid profile in patients at cardiovascular risk
نویسندگان
چکیده
Background: Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are a new class of potent lipid-lowering drugs. Oxidized low-density lipoprotein (ox-LDL) is the key pathogenic factor leading to atherosclerosis. However, its effect on ox-LDL levels has not been clinically reported. For very high-risk Atherosclerotic cardiovascular disease (ASCVD) patients, guidelines propose stricter blood lipid control targets reduce recurrence events.
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ژورنال
عنوان ژورنال: Journal of Clinical Biochemistry and Nutrition
سال: 2023
ISSN: ['0912-0009', '1880-5086']
DOI: https://doi.org/10.3164/jcbn.23-45